Retrotope’s stabilized fatty acid drugs prevent lipid peroxidation damage from propagating, rapidly stopping the toxic chain reaction at its source. Because the fatty acids in membranes turn over rapidly, the dietary substitution of stabilized fatty acids creates cells fortified against damage.
Retrotope’s drug platform, isotopically stabilized PUFAs, are unique in drug discovery. They are based on essential nutrient fats which have no pharmacological effect in the natural form, but, in the deuterated form, are sensitive and specific drugs with highly non-linear reduction of lipid peroxidation damage. Due to the underlying and causative role of radical lipid peroxidation in many diseases of degeneration, Retrotope's compounds are expected to be active across manifold indications without any significant side effects.